When I used to play out I found If I had any charlie before had unless I had a few beers with me id slowly drift away into paranoia and want to hide under the decks, got far too edgy to mix well too.
Done some wicked sets after a good gurner or two, everything flows with very little effort, although the size of my jaw reflects thr level of concentration Im putting in(my eyebrow slowly rises up to the closer I get to a drop
probably my best set ever though was a after a skinfull of beer, a FAT slug of MCat just before I went on and a gurner during the set did a random as fuck mix of bouncy hard house, euro HT, Techno, hard techno and shranz, went down a storm though suprisingly!
In summary drugs and mixing; hit and miss, and save a couple of beers for dutch courage probably best left along.